The Veterinary Record
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The Veterinary Record, Vol 117, Issue 17, 442-443
Copyright © 1985 by British Veterinary Association

Papers & Articles

Effect of xylazine and ketamine on intraocular pressure in horses

CM Trim, GT Colbern, and CL Martin

Intraocular pressure was measured with a MacKay-Marg tonometer in eight horses following auriculopalpebral nerve block and topical application of lignocaine. Measurements were recorded before and after xylazine, 1.1 mg/kg intravenously, every two minutes for 16 minutes after administration of ketamine, 2.2 mg/kg intravenously, and after recovery from anaesthesia. Before xylazine, intraocular pressure was 17.1 +/- 3.9 and 18.4 +/- 2.2 mm Hg in the left and right eyes, respectively. Intraocular pressure tended to decrease after administration of xylazine and ketamine, with a significant decrease in one eye six minutes after injection of ketamine.


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C. S. Dias and A. K. Mitra
Posterior Segment Ocular Pharmacokinetics Using Microdialysis in a Conscious Rabbit Model
Invest. Ophthalmol. Vis. Sci., January 1, 2003; 44(1): 300 - 305.
[Abstract] [Full Text] [PDF]


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Copyright © 1985 British Veterinary Association