Multisystemic eosinophilic epitheliotropic disease in a horse: attempted treatment with hydroxyurea and dexamethasone

Department of Veterinary Medicine, University of Bristol School of Veterinary Science, Langford.

Equine multisystemic eosinophilic epitheliotropic disease is rare in horses. The clinical signs vary according to the organs affected, the skin and gastrointestinal tract being most commonly involved. This paper gives the first reported description of a horse with multisystemic eosinophilic epitheliotropic disease in the United Kingdom and the attempts to treat it. The horse showed dermatological, gastrointestinal, hepatic, pulmonary and pancreatic involvement. Some improvement was seen when the horse was treated with corticosteroid and hydroxyurea.

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				K. Singh, T. C. Holbrook, L. L. Gilliam, R. J. Cruz, J. Duffy, and A. W. Confer Severe pulmonary disease due to multisystemic eosinophilic epitheliotropic disease in a horse. Vet. Pathol., February 1, 2006; 43(2): 189 - 193. [Abstract] [Full Text] [PDF]