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The Veterinary Record, Vol 138, Issue 21, 518-519
Copyright © 1996 by British Veterinary Association

Papillary ductal adenocarcinoma in the mammary glands of two horses

G. P. Reppas BVSc, DipVetPath, FACVSc, MRCVS1, S. A. McClintock BVSc, MVetClinStud, MACVSc1, P. J. Canfield BVSc, PhD, MRCPath, FACVSc, MRCVS2, and G. F. Watson MBBS, FRCPA3

1 Rural Veterinary Centre, Department of Animal Health, University of Sydney, Camden, New South Wales 2570, Australia
2 Department of Veterinary Pathology, University of Sydney, Sydney, New South Wales 2006, Australia
3 Department of Anatomical Pathology, Royal Prince Alfred Hospital, Missenden Road, Camperdown, New South Wales 2050, Australia

Mammary gland neoplasms in horses are uncommon and may initially be confused with mastitis. Masses from the mammary glands of two horses with chronic discharges were examined by cytology and histopathology. Both masses were diagnosed as papillary ductal adenocarcinomas with extensive intraductal and intralobular involvement and only focal infiltration of the adjacent stroma. Complementary immunohistochemical studies were made of both fresh and formalin-fixed tumour tissue, and attempts were made to assess the steroid receptor status of fresh tissue biochemically to assess the possibility of hormonal treatment as an adjunct to surgery. The results of these tests for oestrogen and progesterone receptors were negative.




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K. Hirayama, Y. Honda, T. Sako, M. Okamoto, N. Tsunoda, M. Tagami, and H. Taniyama
Invasive Ductal Carcinoma of the Mammary Gland in a Mare
Vet. Pathol., January 1, 2003; 40(1): 86 - 91.
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Copyright © 1996 British Veterinary Association