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The Veterinary Record, Vol 139, Issue 2, 41-43
Copyright © 1996 by British Veterinary Association

Pergolide treatment for Cushing's syndrome in a horse

M. C. Muñoz Dvm, PhD1, F. Doreste DVm1, O. Ferrer DVm, PhD1, J. González DVM1, and J. A. Montoya DVM, PhD1

1 Departamento de Patología Animal, Facultad de Veterinaria de la Universidad de Las Palmas de Gran Canaria, C/Fco Inglott Artiles, 12-A, 35016 Las Palmas de Gran Canaria, Spain

A 16-year-old, male, Hanoverian horse had a three-month history of weight loss, hirsutism and polyuria/polydypsia. Examinations revealed neutrophilia, lymphopenia, hyper glycaemia and abnormalities in hepatic function. A tentative diagnosis of hyperadrenocorticism was made. The results of thyroid-releasing hormone and combined dexamethasone suppression and ACTH stimulation tests suggested the presence of a pituitary adenoma. The horse was treated with pergolide and benefical clinical and biochemical responses were observed within one to six months.






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Copyright © 1996 British Veterinary Association