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The Veterinary Record, Vol 142, Issue 24, 662-665
Copyright © 1998 by British Veterinary Association

Canine distemper antibodies in lions of the Masai Mara

R. Kock MA, MRCVS1, J. Wambua BVM1, J. Mwanzia BVM, MVPH1, W. S. K. Chalmers BSc, PhD, MIBiol2, C. Chillingworth 2, W. Baxendale BVM&S, MRCVS2, and P. G. Coleman BA3

1 Veterinary Unit, Kenya Wildlife Services, Nairobi, Kenya
2 Intervet (UK) Ltd, The Elms, Houghton, Cambridgeshire PE17 2BQ
3 London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT

Canine distemper virus (CDV) has been implicated in some recent deaths of lions, which showed clinical signs of distemper, in the the Serengeti plain. Similar clinical findings have since been reported in lions of the Masai Mara. Fifty-five per cent of serum samples obtained from wild lions of the Masai Mara have been found to contain neutralising antibody to CDV, indicating that they had been exposed to the virus. Adult orphan lions kept in captivity, were vaccinated with the live attenuated Onderstepoort strain of CDV. The results indicated that the vaccine is both safe and immunogenic, and may be potentially useful for the prophylactic vaccination of lions at high risk.




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