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The Veterinary Record, Vol 143, Issue 19, 523-526
Copyright © 1998 by British Veterinary Association

Natural Borna disease virus infection in cats in the United Kingdom

N. A. Reeves BSc1, C. R. Helps BSc, PhD1, D. A. Harbour BSc, PhD1, C. Blundell MRCVS2, P. L. Finnemore 1, G. R. Pearson BVMS, PhD, MRCPath, MRCVS3, and D. A. Gunn-Moore BSc, BVM S, PhD, MRCVS3

1 Division of Molecular and Cellular Biology, University of Bristol School of Veterinary Science, Langford House, Langford, Bristol BS40 5DU
2 Division of Companion Animals, Department of Clinical Veterinary Science, University of Bristol School of Veterinary Science, Langford House, Langford, Bristol BS40 5DU
3 Department of Pathology and Microbiology, University of Bristol School of Veterinary Science, Langford House, Langford, Bristol BS40 5DU

Borna disease virus (BDV) is a novel RNA virus that has only recently been characterised and classified in a new virus family, Bornaviridae. The virus was detected in buffy coat cells from four of five cats with neurological disease and in the brains of five of 15 cats with nervous signs and of one of three cats with non-neurological disease. In a serosurvey of 111 cats the incidence of antibody to BDV in cats with neurological disease was higher than in cats with other types of disease, suggesting that the virus may play a role in nervous diseases of cats in the UK.




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