HOME CURRENT ISSUE TABLE OF CONTENTS ARCHIVE SEARCH SUBSCRIPTIONS JOBS FEEDBACK HELP		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) A correction has been published Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Banting, A. Articles by Mustonen, K. Search for Related Content PubMed PubMed Citation Articles by Banting, A. Articles by Mustonen, K.

Efficacy of oral and parenteral ketoprofen in lactating cows with endotoxin-induced acute mastitis

¹ Bio Logic, Savigne sur Lathan, 37340, France
² Vetcare, PO Box 26, SF 04601 Mantsala, Finland
³ La Bergerie, 37230 St Etienne de Chigny, France

One hind quarter of 27 healthy lactating cows was infused with 100 µg Escherichia coli endotoxin. Two hours later, nine of the cows were given physiological saline by intramuscular injection, nine were given 4 mg/kg ketoprofen orally, and nine were given 3 mg/kg ketoprofen by intramuscular injection. Ketoprofen administered either orally or parenterally significantly reduced the effect of the endotoxin on rectal temperature, ruminal contractions and respiratory rate. The size of the udder, the signs of pain and the concentrations of thromboxane B₂, especially in plasma, were also reduced, and the appearance of their milk was almost normal. The response of cows to the oral treatment was as rapid as it was to intramuscular treatment.