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Serum phosphorus concentrations in dogs with leishmaniosis at different stages of chronic kidney disease

¹ Clínica Veterinaria Germanías, Avinguda de la Republica Argentina 44, 46701 Gandía, Valencia, Spain
² Hospital Clínico Veterinario, Departamento de Medicina y Cirugía Animal, Universidad de Murcia, Murcia, Spain

Correspondence: E-mail for correspondence: germanias{at}telefonica.net

Serum phosphorus concentrations were measured in 155 dogs with leishmaniosis at different stages of chronic kidney disease (CKD), and in 54 healthy dogs. CKD was classified into six stages, as follows: stage 0 (dogs with no evidence of CKD), serum creatinine (SCr) less than 125 µmol/l and urine protein:creatinine ratio (UPC) less than 0·2; stage 1A, SCr less than 125 µmol/l and UPC 0·2 to 0·5; stage 1B, SCr less than 125 µmol/l and UPC over 0·5; stage 2, SCr 125 µmol/l to 180 µmol/l; stage 3, SCr 181 µmol/l to 440 µmol/l; stage 4, SCr over 440 µmol/l. The dogs' serum phosphorus concentrations correlated significantly with the severity of CKD (P<0·001), and hyperphosphataemia (>1·8 mmol/l) affected 12 per cent, 11·8 per cent, 50 per cent, 76·9 per cent and 100 per cent of the dogs at stages 1A, 1B, 2, 3 and 4, respectively.