The Veterinary Record
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The Veterinary Record 165:314-318 (2009)
© 2009 British Veterinary Association

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Innervation of canine skin: an immunohistochemical study

M. Alves de Medeiros, BS, PhD1,4, C. M. Startin2,4 and N. D. Jeffery, BVSc, PhD, CertSAO, DSAS, DECVN, DECVS, FRCVS3

1 Department of Physiological Sciences, Universidade Federal Rural do Rio de Janeiro, BR 465 KM 7, 23890 000, Rio de Janeiro, Brazil
2 School of Biomedical Sciences, Institute of Neuroscience, University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH
3 Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES
4 Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES

Correspondence: Correspondence to Dr Jeffery, e-mail: ndj1000{at}cam.ac.uk

The general appearance of the innervation of samples of skin from 10 young beagles was studied by using the pan-neuronal immunolabel PGP9.5, and quantitative data on the density of the nerve fibres was obtained. The data provide a baseline for the development of a diagnostic test for small fibre neuropathy in domestic dogs.






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