HOME CURRENT ISSUE TABLE OF CONTENTS ARCHIVE SEARCH SUBSCRIPTIONS JOBS FEEDBACK HELP		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Request Permissions Google Scholar Articles by Drexler, C. S. Articles by Thacker, E. L. PubMed PubMed Citation Articles by Drexler, C. S. Articles by Thacker, E. L.

Efficacy of combined porcine reproductive and respiratory syndrome virus and Mycoplasma hyopneumoniae vaccination in piglets

¹ Intervet/Schering-Plough Animal Health, PO Box 31, 5830 AA Boxmeer, The Netherlands
² Department of Veterinary Microbiology and Preventive Medicine, Iowa State University, Ames, IA 50011, USA
³ Animal Health, Agricultural Research Service, United States Department of Agriculture, 5601 Sunnyside Avenue, Beltsville, MD 20705-5148, USA

Correspondence: E-mail for correspondence: christa.drexler{at}intervet.com

Three vaccination challenge studies were performed to evaluate the impact on vaccine efficacy of combining porcine reproductive and respiratory syndrome virus (PRRSV) and Mycoplasma hyopneumoniae vaccines. Piglets were vaccinated with either a M hyopneumoniae bacterin, a modified live PRRSV vaccine based on a European-type PRRSV strain, or a combination of both vaccines, followed by experimental infection with either M hyopneumoniae or PRRSV. Vaccine efficacy was evaluated by assessing lung lesion scores for M hyopneumoniae and measuring viraemia for PRRSV. There were no significant differences between the protective efficacy of the combined vaccine protocol and the protective efficacy of the two single vaccines, indicating that PRRSV vaccination did not interfere with M hyopneumoniae vaccine efficacy and vice versa.